Developing the Etiwanda Intermediate School physical education curriculum through inservices and staff development

Despite having a successful physical education program at Etiwanda Intermediate School the need still remains for a written curriculum that ties in with the California State Framework (1994). The development of this project represents the beginnings of the goal of a written curriculum at Etiwanda Intermediate School. This will be an on-going process, through use of needs assessment surveys, including the teachers at all levels, focus on teaching practices, plenty of hands-on practice, and incentives for teachers. There is also an evaluation form to meet the needs in the ever-changing world of physical education

A MicroRNA that Regulates TLR-Mediated Fibrosis

Hepatic damage can be caused by an array of factors which, if sustained, can lead to hepatic fibrosis.[...

Candidate risks indicators for bipolar disorder:early intervention opportunities in high-risk youth

Background: Psychiatric illnesses like bipolar disorder are increasingly understood to be neurodevelopmental disorders with clinical, psychological, and biological indicators recognizable long before the emergence of the full-blown syndromes. Methods: This paper is a selective review of findings from studies of high-risk children of affected parents that inform the knowledge of illness risk and development markers of bipolar disorder. We specifically focus on candidate clinical, biological, and psychological risk indicators that could serve as targets for future early intervention and prevention studies. Results: There is convergent evidence from prospective studies that bipolar disorder typically debuts as depressive episodes after puberty. In some high-risk children, sleep and anxiety disorders precede mood disorders by several years and reflect an increased vulnerability. An association between early exposure to adversity (eg, exposure to parental illness, neglect from mother) and increased risk of psychopathology may be mediated through increased stress reactivity evident at both behavioral and biological levels. Inter-related psychological processes including reward sensitivity, unstable self-esteem, rumination, and positive self-appraisal are risk factors for mood disorders. Disturbances in circadian rhythm and immune dysfunction are associated with mood disorders and may be vulnerability markers influenced by these other risk factors. Conclusions: There is accruing evidence of a number of measurable and potentially modifiable markers of vulnerability and developing illness in youth at familial risk for bipolar disorder. Longitudinal studies of multiple biological and psychological risk processes in high-risk offspring, both individually and together, will improve our understanding of illness onset and lead to the development of specific early interventions

Reporting methodological search filter performance comparisons : a literature review

© 2014 The authors. Health Information and Libraries Journal © 2014 Health Libraries Journal.Peer reviewedPostprin

Exploring the role of spatial cognition in problem solving

While spatial aptitude is acknowledged as a key cognitive ability that accompanies success in STEM education, less is reported about the qualitative differences between weak and strong visualisers in how they approach and engage with assessments in STEM education. In this paper, we study one particular aspect of the STEM curriculum - solving convergent ‘word’ problems in mathematics - in an attempt to discern quantitative and qualitative differences between the approaches weak and strong visualisers adopt when solving these problems. The paper is a work-in-progress that started with a search for suitable convergent mathematics problems which were then presented to a small sample of engineering students using a think aloud protocol. Participants were asked to think aloud while they solved the problems and to write their answers using a LiveScribe pen to concurrently record spoken and written responses. They also completed a spatial skills test. The magnitude and significance of the correlation between the spatial and mathematics tests scores were measured to be r = .79, p \u3c .01

Preventing disease and saving resources:the potential contribution of increasing breastfeeding rates in the UK

Two challenges stand out as we contemplate the future of health services in the United Kingdom. The first is the state of the public finances and therefore the pressure in real terms on health services funding. The second is the recurring and vexing problem of health inequalities. The state of health inequalities in Britain has been commented on by many, but we have seen precious little real change in the disproportionate burden of early death and illness among the most disadvantaged and indeed across the whole health gradient in recent years.This work was funded by UNICEF UK

Silver Doped Perfluoropolyether-Urethane Coatings: Antibacterial Activity and Surface Analysis

The colonisation of clinical and industrial surfaces with pathogenic microorganisms has prompted increased research into the development of effective antibacterial and antifouling coatings. There is evidence that implanted biomedical surfaces coated with metallic silver can be inactivated by hysiological fluids, thus reducing the bioactivity of the coating. In this work, we report the biofilm inhibition of Staphylococcus epidermidis using a roomtemperatureprocessedsilver dopedperfluoropolyether-urethane coating. The release of silver ions from these fluoropolymers over a six-day period inhibited bacterial encrustation – as observed by scanning electron microscopy (SEM). X-ray photoelectron spectroscopy (XPS) analysis indicated differences in carbon, fluorine and sodium surface composition between silver doped and undoped fluoropolymers after exposure to nutrient rich media. These silver doped perfluoropolyether coatings also exhibited antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA), Escherichia coli, Pseudomonas aeruginosa and Acinetobacter baumannii; suggesting potential use in preventing transmission of pathogenic and opportunistic microbes on environmental surfaces in healthcare facilities. The broad-spectrum antibacterial activity of these silver release coatings may be exploited on biomaterials surfaces to combat the development of resistant Gram-negative Enterobacteriaceae that can occur during prophylactic treatment for urinary tract infections

On the Fly GPS Tide Measurement along the Saint John River

Conventional tide measurement gives a separate reading at each tide gauge but cannot meet completely with the requirement of precise hydrographic survey for points between tide gauges. The GPS differential technique provides an alternative method for obtaining on-the-fly tides, which can only be achieved by applying latency correction, attitude correction, height transformation, draft correction and finally a data filter.La mediciôn convencional de marea proporciona una lectura separada en cada mareôgrafo pero no puede cumplir totalmente et requerimiento de los levantamientos hidrogrâficos precisos para los puntos que se encuentran entre los mareôgrafos. La técnica de GPS diferencial proporciona un método alternativo para la obtenciôn de mareas "al sobrevueio", que puede ser llevado a cabo ûnicamente aplicando la correcciôn de latencia, la correcciôn de actitudes, la transformation de alturas, la correcciôn de caiado y, finalmente, un filtro de datos.Le mesurage des marées traditionnel permet d'obtenir une lecture séparée à chaque marégraphe mais ne peut pas répondre entièrement aux exigences de levés hydrographiques précis pour les points situés entre les marégraphes. La technique du GPS différentiel fournit une autre méthode d'obtention des marées à la volée qui ne peut être réalisée qu 'en appliquant la correction du temps d'attente, la correction de l'attitude, la transformation des hauteurs, la correction du tirant d'eau et enfin un filtre de données

Choosing and using methodological search filters : searchers' views

© 2014 The authors. Health Information and Libraries Journal © 2014 Health Libraries Group.Peer reviewedPostprin

Interleukin-33 contributes to both M1 and M2 chemokine marker expression in human macrophages

Abstract Background Interleukin-33 is a member of the IL-1 cytokine family whose functions are mediated and modulated by the ST2 receptor. IL-33-ST2 expression and interactions have been explored in mouse macrophages but little is known about the effect of IL-33 on human macrophages. The expression of ST2 transcript and protein levels, and IL-33-mediated effects on M1 (i.e. classical activation) and M2 (i.e. alternative activation) chemokine marker expression in human bone marrow-derived macrophages were examined. Results Human macrophages constitutively expressed the membrane-associated (i.e. ST2L) and the soluble (i.e. sST2) ST2 receptors. M2 (IL-4 + IL-13) skewing stimuli markedly increased the expression of ST2L, but neither polarizing cytokine treatment promoted the release of sST2 from these cells. When added to naïve macrophages alone, IL-33 directly enhanced the expression of CCL3. In combination with LPS, IL-33 blocked the expression of the M2 chemokine marker CCL18, but did not alter CCL3 expression in these naive cells. The addition of IL-33 to M1 macrophages markedly increased the expression of CCL18 above that detected in untreated M1 macrophages. Similarly, alternatively activated human macrophages treated with IL-33 exhibited enhanced expression of CCL18 and the M2 marker mannose receptor above that detected in M2 macrophages alone. Conclusions Together, these data suggest that primary responses to IL-33 in bone marrow derived human macrophages favors M1 chemokine generation while its addition to polarized human macrophages promotes or amplifies M2 chemokine expression.http://deepblue.lib.umich.edu/bitstream/2027.42/78250/1/1471-2172-11-52.xmlhttp://deepblue.lib.umich.edu/bitstream/2027.42/78250/2/1471-2172-11-52.pdfPeer Reviewe